Check out the videos from Jamstack Conf Virtual, May 27. Watch the presentations
Take any sources -- Markdown or other documents, API calls, databases, headless CMSs --, process them using sitio helpers or on your own way, then render pages. No need to adjust your files to some predefined pattern or tree structure, place them wherever you want and write your own code that finds them (although some helpers are provided).
You can write dynamic components and embed them in the pages, like placing SPA-like functionality in a section of your site, or embedding maps, pickers, dynamic forms or other kinds of functionality in the middle of a blog article.
Also, only the skeleton (basic components and code) of the site/app is loaded statically, all the data specific for each page is loaded asynchronously and dinamically while the visitor is browsing.